Polysorbate 20 alters the oral bioavailability of etoposide in wild type and mdr1a deficient Sprague-Dawley rats
نویسندگان
چکیده
منابع مشابه
Determination of Oral Bioavailability of Fusaric Acid in Male Sprague-Dawley Rats
Head and neck squamous cell cancer accounts for 3 % of new cancer cases and 2 % of cancer mortality annually in the United States. Current treatment options for most head and neck cancers continue to be surgical excision with or without radiation, radiation alone, or chemotherapy with radiation depending on location, stage of disease, and patient preference. Fusaric acid (FA) is a novel compoun...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Bioavailability and mass balance studies of a commercial pentabromodiphenyl ether mixture in male Sprague-Dawley rats.
Polybrominated diphenyl ethers (PBDE) are common flame retardants used in polyurethane foam, high impact polystyrene, and textiles which appear to be increasing in the environment and biota. Two PBDE congeners that are particularly prominent in environmental samples are 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) and 2,2',4,4',5-pentabromodiphenyl ether (BDE-99). These two congeners are major c...
متن کاملthe effects of oral administration of morphine sulphate on foetuses of sprague-dawley rats
the deleterious effects of morphine sulphate addiction on the central nervous system are welldocumented. previous studies have shown that the passage of morphine from the placenta barrier caninfluence the normal development of embryos, such as those of humans, by specific mechanisms. so, forthe first time, for the purpose of investigating the effects of morphine sulphate on pregnant animals,thr...
متن کاملInduction of type 2 diabetes with high concentration and long term fructose intake in male Sprague-Dawley rats
Introduction: High calorie diet is becoming the most important health problem in most developed western societies. Diets with high caloric contents such as high fructose intake are associated with increasing risk of type two diabetes (T2D) and insulin resistance (IR). However, large differences have been seen in the dose and duration of fructose consumption to induction of T2D. Interest to deve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2018
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2018.04.006